8th RSC/SCI Ion Channels as Therapeutic Targets

8th RSC-BMCS / SCI Symposium on Ion Channels as Therapeutic Targets

Event
8th RSC-BMCS / SCI symposium on Ion Channels as Therapeutic Targets

Dates
31^st March – 1^st April 2025

Place
Hinxton Hall, Wellcome Genome Campus, Cambridge

Important links and downloads
Twitter hashtag – #IonChannels25
Click here to view the second announcement poster.

Registration
Please click here to register.

RSC/SCI Member £390
Non-Member £485
RSC/SCI Student Member £170
Student Non-Member £210

Registration closes Midnight (GMT) 14th March, 2025

Registration fees will include the conference dinner. Limited on-site accommodation is available to book by following the instructions in your registration confirmation email you will receive shortly after registering.

Want to become a member?

In order to qualify for discounted registration at this event please see below:

To join the RSC please follow this RSC link.

To join the SCI please follow this SCI link.

Call for Abstracts
Abstract submission is open, click here to submit your abstract.
Deadline for poster submissions – Midnight (BST) 17th January, 2025.

Bursaries

The RSC-BMCS and SCI are offering a small number of bursaries to attend the meeting in person. Applications are open to PhD and post-doctoral applicants studying at academic institutions or non-profit institutions. Preference will be given to members of the RSC-BMCS and SCI. Bursary applications are also invited from RSC, SCI or EFMC members who are of working age, but currently unemployed and from those who may have difficulty in funding their attendance. The bursary application deadline is Friday 10th January.

Please click here to download the BMCS bursary form.
Please click here to download the SCI bursary form.

Please send all completed application forms to events@hg3.co.uk

Agenda
Monday 31st March

Time	Session Information
10.00 – 10.30	Registration & refreshments
10.30	Opening remarks Mike Clegg, MSD
Session 1	Session chair: Mike Clegg, MSD
10.40 – 11.15	Talk 1 Jack Terrett, Genentech Inc Discovery of TRPA1 Antagonist GDC-6599: A Potential First-in-Class Therapy for Respiratory Disease
11.15 – 11.50	Talk 2 Katie Simmons, University of Leeds Discovery of Novel KCNT1 Ion Channel Inhibitors for the Treatment of Epilepsy
11.50 – 12.25	Talk 3 Stephen Tucker, University of Oxford CryoEM Structure of the THIK-1 (KCNK13) K2P Potassium Channel
12.25 – 13.30	Lunch
Session 2	Session chair: Alex Preston, GSK
13.30– 14.05	Talk 4 Mike Morton, ApconiX Benefits of early in vitro screening for seizure liability in problem solving and decision making
14.05– 14.40	Talk 5 Alison Obergrussberger, Nanion Technologies Emerging electrophysiological tools for studying lysosomal ion channels and transporters as drug targets
14.40-15.00	Flash poster presentations
15.00 – 15.30	Refreshments
Session 3	Session chair: Rose Bardell-Cox, BMCS
15.30 – 16.05	Talk 6 Radu Aricescu, MRC Laboratory of Molecular Biology The wide wild world of human GABAA receptors
16.05 – 16.40	Talk 7 Paul Miller, University of Cambridge Molecular mechanisms of action of antibodies against GABA-A receptors that modulate anxiety
16.40 – 17.15	Talk 8 Trevor Wilkinson, Astrazeneca Modulating Ion Channel Function with Biologics: Opportunities and Challenges
17.15 – 18.30	Networking reception and posters
19.00 – 21.00	Conference Dinner

Tuesday 1st April

Time	Session Information
Session 4	Session chair: Jason Tierney, Medchemica
9.00 – 9.35	Talk 9 Sara Bonvini, Astrazeneca The therapeutic potential of ion channels in cough: what could the future hold?
9.35 – 10.10	Talk 10 Neils Decher, Phillipps University Marburg Potassium channel TASK-5 forms functional heterodimers with TASK-1 and TASK-3 to break its silence
10.10– 10.40	Refreshments
Session 5	Session chair: Sarah Major, Dark Blue Therapeutics
10.40 – 11.15	Talk 11 Thomas Voets, KU Leuven TRPM3 as a therapeutic target for pain and neurological diseases, from structure-function analyses to animal models and drug development
11.15 – 11.50	Talk 12 Anna Moroni, University of Milan Therapeutic approaches to discuss on cardiac and neuronal diseases, related to HCn channels, as well as on neuropathic pain
11.50 – 12.25	Talk 13 Sven Van Brandt, Johnson & Johnson Identification of Selective GluN2A Negative Allosteric Modulator Tools Suitable for in Vivo Exploration
12.25 – 13.25	Lunch
Session 6	Session chair: Brian Cox, University of Sussex
13.25 – 13.35	Poster prizes
13.35-14:10	Talk 14 Late breaker
14.10 - 14.45	Talk 15 Christopher Johnson, Astex Enabling High Throughput Electron Cryo-microscopy for Structure-based Design
14.45– 15.20	Talk 16 Henry Danahay, Enterprise Therapeutics ENaC blocker for the treatment of cystic fibrosis
15.20	Closing remarks Brian Cox, University of Sussex
15:30	Meeting close

Organising Committe

Rose Bardell-Cox (BMCS) Treasurer
Michael Clegg (MSD) Chair
Brian Cox (University of Sussex)
Sarah Major (Dark Blue Therapeutics)
Alex Preston (GSK)
Jason Tierney (Medchemica)

Exhibitor Opportunity – click here to register.
The exhibitor package comprises-
– Stand space measuring 3 metres wide x 2 metres deep
– Table measuring 240cm wide x 80cm deep and chair
– Electrical and wifi access
– One stand personnel
– Your logo and full promotional page in the delegate handbook
– Your logo in the rolling slide, shown during the breaks
– Full attendance at the technical programme, poster sessions and conference evening dinner for stand personnel

£1400.00 including one full delegate

Sponsor Opportunities
Sponsorship includes –
– Your logo in the pre-event announcements
– Your logo in the delegate handbook
– Your logo in the rolling slides, shown during the breaks

Minimum suggested sponsorship amount is £500.00

Sponsored Lanyards – £500.00
– Delegate lanyards with company logo, sponsor provides

Delegate Inserts – £500.00
– -No more than two pages of A4 fixed together, sponsor provides.

Exhibitors