BMCS 5th Synthesis in Drug Discovery and Development 2025
Event
BMCS 5th Synthesis in Drug Discovery and Development
Dates
Tuesday 3rd – Wednesday 4th June, 2025
Place
Virtual (Zoom)
Important links and downloads
Hashtag for X – #SDDD25
Click here to register
Click here to download the first announcement poster
Synopsis
Synthesis is at the heart of drug discovery and development. The industry has increasingly demanded higher quality clinical candidates and has sought to exploit less druggable biological targets. Densely functionalised small molecules with a high degree of synthetic complexity are often the result of these demands. Successful programmes therefore require the application of innovative synthesis in all stages of discovery and development. The medicinal chemist’s toolbox is also enhanced by the introduction of novel bioisosteres, often made available only through the application of new synthetic methods. This symposium aims to celebrate the crucial role of synthesis in the success of drug discovery and development.
Who should attend?
Chemists from industry and academia, including synthetic, medicinal, agroscience, and process chemists.
Want to become a member?
To join the RSC in order to qualify for discounted registration fees at all RSC events, please follow this RSC link.
Registration
Fees:
RSC Member – £50.00
Non-Member – £80.00
RSC Student Member – £25.00
Student Non-Member – £40.00
Please click here to register.
Call for Abstracts
Abstract submission is now closed.
Exhibition/Sponsor Opportunities
Exhibitor package is priced at £100.00 and includes:
– Name and URL link on BMCS event page
– Company logo included in the electronic handbook and rolling slides at the event
– A4 promotional page in the electronic handbook
– Access to the online meeting
Exhibitor plus package is priced at £300.00 and includes:
– Name and URL link on BMCs event page
– Company logo included in the electronic handbook and rolling slides at the event
– A4 promotional page in the electronic handbook
– 3 minute pre-recorded video to be played on loop during the breaks
– Access to the online meeting
Please click here to register for an exhibition package or sponsorship.
Programme
Tuesday 3rd June 2025
| 13.00 | Opening remarks |
|---|---|
| 13.05 - 15.05 | Session 1 Chair: Katherine Jones, Charles River |
| 13.05 | Hossay Abas (Cancer Research Horizons) - Scalable Synthesis of an Acid Analogue of Hippuristanol |
| 13.45 | William Unsworth (University of York) - Ring Expansion Approaches for the Synthesis of Functionalised Heterocyclic Macrocycles and Medium-sized Rings |
| 14.25 | Donatus Bekindaka Eni (University of Buea) - Privileged Scaffold Modification in the Design & Synthesis of Nature-Inspired Bioactive Molecules |
| 15.05 | Refreshment break |
| 15.20 - 16.55 | Session 2 Chair: Hossay Abas, Cancer Research Horizons |
| 15.20 | Hikaru Ishikura (ICL) - New Synthetic Approaches to 1,1-Disubstituted gem-Difluorocyclobutanes as Design Elements for Medicinal Chemistry |
| 15.35 | Angela Russell (University of Oxford) - Development of next generation utrophin modulators for Duchenne muscular dystrophy: an integration of chemical biology and drug discovery |
| 16.15 | Claudio Bomio-Confaglia (Novartis) - Adventures in Atropisomerism - Discovery and Optimization Challenges in the Synthesis of JDQ443: A Novel KRASG12C Inhibitor |
| 16.55 | Close |
Wednesday 4th June 2025
| 13.00 - 15.05 | Session 3 Chair: Pradip Songara, Rothamsted |
|---|---|
| 13.05 | Andrew Lister (AstraZeneca) - Milligrams to Kilograms: Frontloading Synthesis to Enable Rapid Profiling and Shortlisting of EGFR Exon20 Inhibitors |
| 13.45 | Stuart McHale (University of York) - Stereospecific Csp3-Csp2 Suzuki-Miyaura Cross-Coupling of Secondary Heterocyclic Boronates |
| 14.25 | Joe Harrity (University of Sheffield) - Cyclisation and Cycloaddition Strategies Towards Functionalised Building Blocks |
| 15.05 | Refreshment break |
| 15.20 - 16.35 | Session 4 Chair: Andrew Williams, RSC BMCS |
| 15.20 | Mark Berney (Queen’s University Belfast) - Zinc-Binding Oligonucleotides for Targeting a Metalloenzyme Involved in DNA Repair |
| 15.35 | Karandip Saini (University of Leeds) - Small Bicyclic Amines: Unexplored Motifs for Drug Discovery |
| 15.50 | Xiayun Cheng (Pfizer) - Synthetic Innovation as the Driving Force in Medicinal Chemistry Project Delivery |
| 16.30 | Closing remarks |
| 16.35 | Close |
Exhibitors
Sponsors
Organising Committee
Katherine Jones, Charles River (Chair)
Martin Swarbrick, Ryvu Therapeutics (Treasurer)
Andrew Williams, RSC BMCS
Pradip Songara, Rothamsted Research
Secretariat Contact and Further Information
Hg3 Conferences Ltd
+44 (0)1423 529333
E-mail
