4th RSC Anglo-Nordic Medicinal Chemistry Symposium
Event
4th RSC Anglo-Nordic Medicinal Chemistry Symposium
X hashtag – #ANMC2025
Dates
Tuesday-Friday, 10th-13th June 2025
Place
Hotel Comwell Borupgaard, Snekkersten, Denmark
Who should attend?
Medicinal chemists at all career stages. Scientists with an interest in drug discovery or new technologies that can be applied to the drug discovery process.
Synopsis
This 2.5 day symposium is the fourth in the very successful series of biannual meetings started in 2017 containing high quality international speakers from industry and academia on topics of Medicinal Chemistry and related enabling technologies. Organised by the Biological and Medicinal Chemistry Sector of the Royal Society of Chemistry, together with Nordic affiliates, the meeting promises to be an exciting and invigorating gathering packed with fantastic opportunities to disseminate knowledge and expand networks.
The event will include first rate lectures, poster session, trade exhibition, ample networking opportunities, welcome buffet on Tuesday, exceptional location, venue and accommodation.
Call for Papers
The oral and poster submission is now open, please click here to submit your abstract.
The deadline for oral abstracts is Friday 31st January 2025
The deadline for poster abstracts is Thursday 1st May 2025
Registration
Registration is now open! Click here to register.
Early bird registration deadline is 28th March, 2025
Registration deadline: 2nd June, 2025
Registration Fees
Early bird rate
RSC Member £560.00
Non-Member £670.00
RSC Student** Member* £420.00
Student** Non-member (undergraduate and post-graduate) £510.00
Late registration rate
RSC Member £615.00
Non-Member £730.00
RSC Student** Member* £475.00
Student** Non-member (undergraduate and post-graduate) £570.00
* Member is a paid-up member of the RSC
** Student rates apply to undergraduate and post-graduate students only, but not post-doctoral students.
The registration rate includes attendance at the conference and lunch meals only, with additional packages available to book for accommodation and conference dinners.
Accommodation and Dinners Package
The Accommodation and Dinners Package is available for an additional cost of £750 and includes:
– three nights’ bed and breakfast accommodation at the conference Hotel Comwell Borupgaard (from Tuesday to Thursday inclusive)
– three-course dinner with drinks on Wednesday
– conference dinner with drinks on Thursday
It will be advisable to book this at the time of registration.
Dinner and Drinks Package
A dinner and drinks package is available for an additional cost of £255 and includes the following:
– Dinner and drinks on Wednesday
– Conference dinner and drinks on Thursday
A Conference Dinner ticket only is also available for £95
Student Bursaries
The RSC-BMCS are offering a small number of bursaries to attend the meeting in person. Applications are open to PhD and post-doctoral applicants studying at academic institutions or non-profit institutions. Preference will be given to members of the RSC-BMCS. Bursary applications are also invited from RSC or EFMC members who are of working age, but currently unemployed and from those who may have difficulty in funding their attendance. The bursary application deadline is Friday 21st March 2025.
Please click here to complete the application form.
Please send all completed application forms to events@hg3.co.uk
Want to become a member?
To join the RSC in order to qualify for discounted registration fees at all RSC, please follow this RSC link.
Exhibitor Opportunities
The exhibition packages are now sold out. If you would like further information on sponsoring this meeting please contact chloe.naylor@hg3.co.uk .
Venue
Address: Hotel Comwell Borupgaard, Nørrevej 80, Snekkersten 3070, Denmark
Venue website (showing location)
Travel
These are guide prices which you should verify for yourself, please.
By train: 55 minutes from Copenhagen airport/railway station to Snekkersten. Cost £10-£17
By taxi: 45 minutes from Copenhagen airport/railway station to Snekkersten. Cost £95-£100
By bus and train: 1h 50m from Copenhagen airport/railway station to Snekkersten. Cost £7-£20
Danish travel information website
This is a map with travel modes and charges from Copenhagen station.
Programme
Tuesday 10th June 2025
| 18:00 - 21:00 | Welcome reception, Registration and Buffet dinner at Restaurant Borupgaard |
|---|
Wednesday 11th June 2025
| 08:30 | Registration Opens |
|---|---|
| 09:15 - 09:30 | Opening of Meeting |
| Session 1 | |
| 09:30 – 10:30 | Discovery of CFTR modulators for the treatment of Cystic Fibrosis Sabine Hadida (Vertex) |
| 10:20 – 10:55 | Discovery of a Topical Preclinical Candidate with Dual ITK and TRK Kinase Inhibition Brian Gestenberger (Pfizer) |
| 10:55 – 11:25 | Refreshment break |
| 11:25 – 12:00 | Drug Design: How is AI changing the game? Rebecca Paul (Isomorphic labs) |
| 12:00 – 12:35 | Structure-based Discovery and Development of Highly Potent Dihydroorotate Dehydrogenase Inhibitors for Malaria Chemoprevention Zhe Nie (Schrödinger) |
| 12:35 – 14:00 | Lunch |
| 14:00 – 14:30 | Flash Poster Session |
| 14:30 – 15:30 | Poster and Schrödinger workshop |
| 15:30 – 16:30 | Posters and Refreshments |
| Session 2 | |
| 16:30 – 17:05 | Discovery of MK-8527: A Novel Nucleoside Reverse Transcriptase Translocation Inhibitor for Long-acting HIV Pre-exposure Prophylaxis Izzat Raheem (Merck) |
| 17:05 – 17:40 | Property-based design of long-acting injectable drugs – a case study Thomas Ullrich (Novartis) |
| 17:40 – 18:25 | Medicinal chemistry and chemical biology of sterol transport proteins Luca Laraia (DTU Kemi) |
| 18:25 - 19:00 | Free time |
| 19:00 | Dinner |
Thursday 12th June 2025
| 08:30 | Registration Opens |
|---|---|
| Session 3 | |
| 09:10 – 09:45 | Discovery and in vivo exploration of 1,3,4-Oxadiazole and a-Fluoroacrylate containing IL-17 inhibitors Nina Gommermann (Novartis) |
| 09:45 – 10:20 | Muvalaplin: A promising oral inhibitor of Lp(a) formation in Clinical Trials Nuria Diaz (Lilly) |
| 10:20 – 10:50 | Refreshment Break |
| Session 4 | |
| 10:50 – 11:25 | DEL screening identifying MTA co-operative inhibitors of PRMT5 Sanne Glad (Amgen) |
| 11:25 – 12:00 | The medicinal chemistry discovery story of AZD3470; an MTA-cooperative PRMT5 inhibitor in clinical evaluation as a cancer treatment James Smith (AstraZeneca) |
| 12:00 – 13:30 | Lunch |
| Session 5 | |
| 13:30 – 14:05 | AZD0780 – an oral PCSK9 inhibitor with a novel mode of action for the prevention of cardiovascular disease Gavin O’Mahoney (AstraZeneca) |
| 14:05 – 14:40 | Advancements in NMDA Receptor-Targeted Antidepressants: From D-Cycloserine Discovery to Preclinical Efficacy of Lu AF90103 Erhad Ascic (Lundbeck) |
| 14:40 – 15:10 | Refreshment Break |
| 15:10 – 15:45 | Discovery of the first apo-form dual IDO1/TDO2 inhibitors achieving full reduction in kynurenine pathway-derived immunosuppressive metabolites in a tumor mouse model Sylvaine Cren (Idorsia) |
| 15:45 – 16:20 | Optimisation of Allosteric ERAP1 Inhibitors Using Automated Molecular Design Daniel Barker (GSK) |
| 16:20 – 17:00 | Refreshments and Posters |
| 17:00 – 18:00 | What does success mean for you? Lessons Learned Looking Back (and Forward) on a Career in Medicinal Chemistry Chris Helal (Biogen) |
| 19:00 | Conference dinner and poster prizes |
Friday 13th June 2025
| 08:30 | Registration Opens |
|---|---|
| Session 6 | |
| 09:00 – 09:35 | Discovery of a unimolecular GLP-1 and amylin receptor agonist: Interplay between medicinal chemistry and new process technologies Felix Wojcik (Novo Nordisk) |
| 09:35 – 10:10 | DNA-Encoded Libraries and High Throughput Screen identified Respiratory Syncytial Virus Polymerase Inhibitors with New Binding Modes Minh Thao Tran (JNJ) |
| 10:10 – 10:45 | Refreshment Break |
| 10:45 – 11:20 | Accelerating PROTAC Discovery: A Direct-to-Biology Approach Using Orthogonally Reactive Linkers for the Identification of a CNS-Active Degrader Andreas Holmqvist (Centre for Targeted Protein Degradation) |
| 11:20 – 11:55 | Heterobifunctional small molecule degraders of extracellular targets Simon Glerup (Draupnir Bio) |
| 11:55 – 12:30 | Expanding the druggable proteome using next-generation covalent chemical probes Lyn Jones (Harvard University) |
| 12:30 – 12:35 | Closing remarks |
| 12:35 | Lunch and depart |
Organising Committee
Sharan Bagal (chair), AstraZeneca, UK
Kevin N Dack, LEO Pharma, DK
Adrian Hall (treasurer), UCB, BE
Malin Lemurell, AstraZeneca, SE
Anette Graven Sams, Lundbeck, DK
Morten Jørgensen, LEO Pharma, DK
Garrick Smith, Amgen Research Copenhagen, DK
Secretariat Contact and Further Information
Hg3 Conferences Ltd
+44 (0)1423 529333
E-mail
Invited Speakers:
Check back here soon for schedule of speakers!
Exhibitors/Sponsors:
