Events

Postgraduate Symposium XVIII – Biological and Medicinal Chemistry Symposium for Postgraduates

Event
Postgraduate Symposium XVIII – Biological and Medicinal Chemistry Symposium for Postgraduates

Date
Thursday 12th December, 2024

Place
The Medical Sciences Teaching Centre, University of Oxford, South Parks Rd, OxfordOX1 3PL

Downloads and Links
X hashtag – #BMCSPostGrad24
To submit your Abstract, click here 
To register, click here
To Exhibit/Sponsor, click here

Synopsis
This face to face meeting will comprise of oral and poster presentations from PhD students and post-doctoral workers researching in biological or medicinal chemistry. In addition, the agenda will feature invited keynote speakers from industry and academia.

Registration
Registration is now open! Click here to register.

This is a free symposium for PhD students, post-doctoral workers, academics and industry workers.

Who should attend
This conference will be of interest to PhD students, post-doctoral workers, academics and industry workers.

Want to become an RSC member?
To join the RSC in order to qualify for discounted registration fees at all RSC events, please follow this RSC link

Call for Abstracts
Abstract submission for oral, flash talks and poster presentations is now open. The deadline for abstract submissions is Midnight (BST), Friday 4th October, 2024, click here to submit your abstract.

Programme

08.30Registration opens, exhibition and refreshments
09.30Welcome and housekeeping announcement
Angela Russell
09.35Opening Remarks
John Skidmore
Session 1Chair: Thomas Lanyon-Hogg
09.40Keynote Lecture
X-ray crystallographic fragment screening for the identification of allosteric binding sites
Dr Louise Walsh, Astex Pharmaceuticals
10.10Postgraduate Talk 1
High-Throughput Modular Syntheses and Biological Evaluation of Structurally-Diverse Reactive Fragment Libraries
Mr Julian Chesti, University of Leeds
10.30Postgraduate Talk 2
Synthesis and vectorial functionalisation of unexplored N-heterocycles for fragment-based drug discovery
Miss Elizabeth Bedwell, Durham University
10.50 - 11.20Refreshment break and exhibitions
Session 2Chair: Katherine Jones
11.20Postgraduate Talk 3
The Development of Next-Generation Reactive Electrophiles for Beyond Cysteine Covalent Drug Discovery
Mr Alfred Doherty, University of Strathclyde
11.40Student flash poster presenations
11.40 FT01 Establishing a chemical biology toolbox to unravel the function of NUDIX family proteins
Mr Haozhe Xiao, University of Oxford, UK

11.42 FT02 Synthesis and Antischistosomal Structure-Activity Relationship Profiling of N-Pyridazin-3-ylbenzamides
Mr Harrison Banda, University of Zambia, Zambia

11.44 FT03 Can LLMs generate good molecules?
Dr Max Jakobs, DeepMirror, UK

11.46 FT04 Selective CDK12 Inhibitors to Treat Myotonic Dystrophy Type 1 (DM1)
Mr John Fox, University of Nottingham, UK

11.48 FT05 A Platform for the High-Throughput Screening of Reactive Fragments in Cells
Mr James Rowley, University of Strathclyde, UK

11.50 FT06 Synthesis of Next Generation Inhibitors of NorA Efflux Pumps to Potentiate Antibiotics
Dr Thomas Burden,Imperial College London ,UK

11.52 FT07 Identification of mild mitochondrial uncouplers and the role of transbilayer proton transport rate.
Mr Ethan Pacchini, University of Technology Sydney, Australia

11.54 FT08 A novel class of thapsigargin-derived broad-spectrum antivirals
Mr Benjamin Owen ,University of Nottingham, UK

11.56 FT09 Design, Synthesis, Molecular Dynamic and Quantum Chemical Parameter (DFT) Analysis of New Pyrazole Derivatives Targeting EGFR for Anticancer Activity Against Breast Cancer
Ms Shaheen Ali, Jamia Hmadard University, India

11.58 FT10 Design of Novel Inhibitors for SARS-CoV-2 Nsp3 Macrodomain
Mr Xinyu Wang, University of York, UK

12.00 FT11 Targeting PfCLK3 with Covalent Inhibitors: A Novel Strategy for Malaria Treatment
Miss Skye Brettell, University of Glasgow, UK

12.02 FT13 RaPID Discovery of Covalent Cyclic Peptide Binders
Mrs Issy Mathiesen,Francis Crick Institute, UK

12.04 FT14 Discovery & characterisation of functional Tools for studying OTUB1
Mr Jack Dainton, Imperial College London, UK

12.06 FT15
Withdrawn

12.08 FT16 Development of Potent Poly (ADP-ribose) Polymerase 1 (PARP1) Degraders for Treating Cancers
Mr Harashkumar V T, Vellore Institute of Technology, India

12.10 FT17 Discovery and Synthesis of Selective Binders of a Plasmodium WD40 Repeat Protein as a Novel Drug Class
Mr Mohsen Alamoudi, School of Pharmacy UCL, UK

12.12 FT18
Withdrawn

12.14 FT19 An automated chemoproteomic platform for deubiquitinase probe and inhibitor discovery in cells
Miss Jiaying Zhuang, Imperial College London, UK

12.16 FT20 Synthesis, in silico and in vitro Antimicrobial Efficacy of some Amidoxime-Based Benzimidazoles and Benzimidamide motifs
Dr Gbolahan Oduselu, Covenant University Bioinformatics Research (CUBRe), UK

12.18 FT21 Covalent warhead optimisations of the metallo-beta-lactamase inhibitor Aspergillomarasmine A
Mr Jack Bradley, University of Liverpool, UK

12.25Lunch, poster session and exhibition
Session 3Chair: Rose Bardell-Cox
13.35Keynote lecture: From antimalarials to antibody-drug conjugates: translating basic science into cancer therapeutics
Ed Tate, Imperial College London
14.05Postgraduate Talk 4
Design and Synthesis of Heterocyclic Aminothiadiazoles as Analogues of Fast Acting 1,3,4-Oxadiazole Based Antimalarials
Dr Charlie Qie, University of Liverpool
14.25Postgraduate Talk 5
Development of an inhibitor of the mutagenic SOS response that suppresses the evolution of quinolone antibiotic resistance
Mr Jacob Bradbury, Department of Pharmacology, University of Oxford
14.45 - 15.05Refreshment break and exhibition
Session 4Chair: Mary Wheldon
15.05Postgraduate Talk 6
Exploring Pain Relief: Dual Mechanism Compounds for Inhibiting Soluble Epoxide Hydrolase and Sigma-1 Receptors
Ms Celia Escriche, University of Barcelona
15.25Postgraduate Talk 7
Autonomous phenotype-directed discovery of chemical probes
Miss Niamh Morris, Rosalind Franklin Institute
15.45Keynote lecture
Embracing Sustainability in a Small Chemistry Department
Dr Verity Sabin, Cancer Research Horizons, UK
16.15Closing Remarks
Mary Wheldon
16.25Wine mixer & prizes
17.00Meeting close

Sponsorship – click here to sponsor
There is no registration fee for this symposium and we are therefore seeking sponsorship from companies towards running the costs.
All sponsor logos will be displayed on the holding slides, pdf of the delegate handbook and included in the communications to delegates.

Exhibition – *FULLY BOOKED*
The exhibition stand package includes:

– A six foot trestle table and chair(s)
– Access to electricity and wi-fi
– Logo inclusion in pdf delegate handbook, rolling slides and event website
– Exhibitor’s promotional page in the pdf delegate handbook
– One stand personnel

Exhibitors

 

 

 

 

Sponsors

 


Organising Committee
Rose Bardell-Cox, Evotec (Treasurer)
Katherine Jones, Charles River
Tom Lanyon-Hogg, University of Oxford
Angela Russell, University of Oxford
John Skidmore, University of Cambridge
Mary Wheldon, University of Dundee (Chair)
Douglas Williamson, Nxera Pharma

Secretariat Contact and Further Information
Hg3 Conferences Ltd
+44 (0)1423 529333
E-mail