34th Medicinal Chemistry in Eastern England

Event
34th Medicinal Chemistry in Eastern England

Dates
Thursday, 27th April 2023

Place
Fielder Centre, Hatfield

Important links
Twitter hashtag – #HatfieldMedChem23
First Announcement poster
Second Announcement poster

Synopsis
Known colloquially as the “Hatfield MedChem” meeting, this is a highly successful, long-standing, one-day meeting that runs annually. The scientific program will comprise presentations showcasing medicinal chemistry case studies from tools to candidates, across a range of modalities, therapeutic areas and target classes, as well as covering more general topics at the forefront of drug discovery. The meeting aims to be informal and interactive, and is ideal for all those working in medicinal chemistry and drug discovery more widely.

Programme

9:00	Registration
	MORNING SESSION Chair: Simon Ward, Medicines Discovery Institute, Cardiff University, UK
09:30	Welcome and Introduction
09:40	Identification of H4R Antagonist HTL0032547 as a potential therapy for Atopic Dermatitis Charlotte Fieldhouse, Heptares, UK
10:20	Optimisation of aminofurazans leading to orally bioavailable and CNS penetrant inhibitors of MSK-1 (Mitogen and Stress-Activated Kinase 1) Anne Valade, UCB, Belgium
11:00	Refreshments
11:30	Isoform-Selective EPAC Activators: Therapeutic Opportunities for Cardiopulmonary Inflammation Graeme Barker, Heriot-Watt University, UK
11:55	Discovery of novel LpxA inhibitors targeting Pseudomonas aeruginosa Alastair Parkes, Evotec, UK
12:20	Electrostatic Complementarity in Structure-Based Drug Design James Day, Astex, UK
12:45	Lunch
	AFTERNOON SESSION Chair: Margarita Puente-Felipe, GSK, Spain
14:15	Next Generation Antibody-Drug Conjugates David Spring, Cambridge University, UK
14:55	AI-driven approach to the discovery of novel Mpro inhibitors with high pan-coronavirus activity Marco Derudas, ExScientia, UK
15:20	Refreshments
15:50	Combining surface chemistry with affinity selection mass spectrometry accelerates drug discovery for protein and oligonucleotide targets Zachary Gurard-Levin, SAMDI Tech a Charles River company, US
16:15	Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRASG12C Doyle Cassar, AstraZeneca, UK
16:55	Concluding Remarks
17:00	Meeting Close

Registration
Registrations are now closed!

Registration Fees
RSC Member* £135
Non-Member £185
RSC Student ** Member* (Undergraduate and post-graduate) £65
Student** Non-Member (Undergraduate and post-graduate) £95
Unemployed Member £65
Unemployed Non-Member £95
Retired Member £40

* Member is a paid-up member of the RSC
** Student rates apply to undergraduate and post-graduate students only, but not post-doctoral students.

Sponsorship Opportunities

Registrations are now closed!

The Exhibitor Package is priced at £500 and includes: EXHIBITION STANDS ARE NOW FULLY BOOKED

– A six foot trestle table and chairs
– Access to electricity and wi-fi
– Logo inclusion in pdf of delegate handbook, website and rolling slides
– Exhibitors promotional page in a pdf delegate handbook
– One stand personnel with access to technical sessions

We are also seeking sponsorship from organisations supporting the low registration fees offered to students. You can support and sponsor this meeting by clicking the booking link above.

Sponsors
We are grateful to our confirmed sponsors for their valued support.