33rd Medicinal Chemistry in Eastern England

33rd Medicinal Chemistry in Eastern England

Thursday, 28th April 2022

Fielder Centre, Hatfield

Important links and downloads
Twitter hashtag – #HatfieldMedChem22
First announcement poster
Second announcement poster
To view RSC Covid-19 policy, click here

Known colloquially as the “Hatfield MedChem” meeting, this a highly successful, long-standing, one-day meeting which runs annually. The scientific program will comprise presentations showcasing medicinal chemistry case studies from tools to candidates, across a range of modalities, therapeutic areas and target classes, as well as covering more general topics from the forefront of drug discovery of relevance to medicinal chemists.

Registration is now closed!

Registration fees:
RSC Member* £125
Non-member £175
RSC Student** Member* £55
Student** Non-member £95
Retired member* £20

* Member is a paid-up member of the RSC 
** Student rates apply to undergraduate and post-graduate students only, but not post-doctoral students.

Want to become a member?
To join the RSC in order to qualify for discounted registration fees at all RSC, please follow this RSC link.

Student Bursaries
The RSC BMCS are offering some student bursaries to attend this meeting in person. Applications are open to PhD and post-doctoral applicants studying at academic institutions. Preference will be given to members of the RSC, a National Adhering Organisation of the EFMC, and any co-sponsoring organisation. The bursary value for this event is up to £300.

Applications for bursaries are now closed.

Exhibition/Sponsorship Opportunities
Bookings are now open, click here to book an exhibitor stand, or sponsor the meeting!

*Exhibitor Stands Fully Booked*

The Exhibitor Package is priced at £250 and includes:
– A six foot trestle table and chair(s);
– A blue baize table cloth;
– Access to electricity and Wi-fi;
– Logo inclusion in delegate handbook and rolling slides;
– Exhibitors promotional page in the printed delegate handbook.

£75 Exhibitor stand personal rate (no access to the technical sessions)
£120 Delegate pack inserts

We are also seeking sponsorship from organisations supporting the low registration fees offered to students. You can support and sponsor this meeting by clicking the booking link above.


9.00Registration and refreshments
9.30Morning Session Chair: Alison Jones, Charles River

Welcome and Introduction
9.35S01 The discovery of novel GPR52 agonists: HTL0041178, a potential therapy for schizoaffective and related psychiatric disorders
Steve Watson, Heptares
10.10S02 Discovery and development of first-in-class USP19 inhibitors for the treatment of metabolic and muscle-wasting disease
Shane Rountree, Almac Discovery
10.45Refreshments, Exhibition and Networking
11.10S03 Development and characterisation of 2-imino-hexahydropyrimidin-4-one derived Plasmepsin X inhibitors with in vivo anti-malarial activity
Teresa de Haro, UCB
11.45S04 The Development of PROTACs at LifeArc
Martin Ambler, Evotec
12.10S05 Discovery and optimisation of allosteric inhibitors of Glutaminase 1 (GLS1)
Mark Charles, Cancer Research UK
12.35Lunch, Exhibition and Networking
13.30S06 Afternoon Session Chair: Simon Ward, Medicines Discovery Institute, Cardiff University

Capps Green Zomaya Award presentation lecture
Applying AI: From Target Discovery through Drug Design to Patient Selection
Jérémy Besnard, Exscientia
14.05S07 Development of MAP4K4 Inhibitors for the Suppression of Cardiac Muscle Cell Death
Nick Martin, Domainex
14.40S08 Accelerating decision making through parallel med chem
Neal Fazakerley, GSK
15.05Refreshments, Exhibition and Networking
15.30S09 Next generation estrogen receptor degraders (SERDs): A decade of discovery at AstraZeneca
Samantha Hughes, AstraZeneca
16.05S10 Discovery of novel LasB inhibitors as an inhaled antivirulence therapy for the treatment of Pseudomonas aeruginosa infections in patients with chronic respiratory disease
David Davies, Antabio
16.30S11 Discovery of DDU209: a potent and selective inhibitor of Lysyl tRNA synthesis
Laura Cleghorn, Dundee Drug Discovery Unit, Univ Dundee
16.55Concluding Remarks
17.00Meeting close

We are grateful to our confirmed sponsors for their valued support.

Domainex logo

We are grateful to our confirmed exhibitors for their valued support.

Organising Committee
Nicole Hamblin, Charles River (Chair)
Adrian Hall, UCB (Treasurer)
David Hirst, MSD

Secretariat Contact and Further Information
Hg3 Conferences Ltd
+44 (0)1423 529333