RSC-BMCS Targeted Protein Degradation: “Three’s a crowd?”

RSC-BMCS Targeted Protein Degradation: “Three’s a crowd?”

Wednesday 16th – Thursday 17th November 2022
Both days will take place in the afternoon from 1 PM – 5 PM (GMT).


Important links
Twitter hashtag – #ProtDeg22

Targeted protein degradation is a rapidly developing field of drug discovery which is expanding the proportion of human proteins which are tractable drug targets. Whereas conventional small molecules are designed to block the activity of a protein, targeted protein degraders act by harnessing biological pathways to remove the protein entirely. This conference will showcase presentations showing the application and development of degradation technologies such as molecular glues and heterobifunctional degraders (e.g. PROTACs)

Who should attend
This conference is aimed at scientists including medicinal and computational chemists, structural and chemical biologists etc., and will be suitable for both those who are experienced in the field of targeted protein degradation and those who are keen to learn more about this rapidly developing field. This new conference is running in a virtual format, and we welcome an international audience of guests and speakers. The sessions are running in the afternoon UK time, and are therefore also easily accessible for a North and South American audience.

Call for Abstracts
Abstract submission is open now. Please click here to submit your oral abstract.

Confirmed Speakers

Challenges and opportunities in Targeted Protein Degradation drug discovery
Elisabetta Chiarparin, AstraZeneca

Driving Drug Discovery by Accelerated Target Degradation
Matt Clifton, Novartis

Title TBC
Mary Matyskiela, Neomorph

Advances and future opportunities in cereblon-mediated molecular glue
Jennifer Riggs, BMS

Molecular Glue Degraders: From Serendipity to Rational Design
Owen Wallace, CSO, Monte Rosa Therapeutics

Discovery and characterization of potent degraders of IRAK4 and IMiD substrates for oncology indications
Yi Zhang, Kymera

Registration is now open, and may be accessed by clicking here. You may pay by card or request an invoice for settlement by bank transfer. Registration fees are:

RSC Member* £75.00
 Non-member  £110.00
 RSC Student** Member* (Undergraduate and Post-Graduate)
 Student** Non-Member (Undergraduate and Post-Graduate)

Registration closing dates:
Online registration (card payments): Wednesday 2nd November 2022 at 17:00 (GMT)
Registration against invoice (bank transfers): Friday 14th October 2022 at 17:00 (GMT)

* Member is a paid-up member of the RSC
** Student rates apply to undergraduate and post-graduate students only, but not post-doctoral students.

Our Exhibitors/Sponsors
We are grateful to our confirmed exhibitors/sponsors for their valued support.



Organising Committee
Adrian Hall, UCB
Katherine Jones (chair), Charles River
Fabian Lecomte (treasurer), Ferring Pharmaceuticals

Secretariat Contact and Further Information
Hg3 Conferences Ltd
+44 (0)1423 529333