Events

Postgraduate Symposium XVI – Biological and Medicinal Chemistry Symposium for Postgraduates 2022

Event
Postgraduate Symposium XVI – Biological and Medicinal Chemistry Symposium for Postgraduates

Date
Friday, 9th December 2022

Place
The Medical Sciences Teaching Centre, University of Oxford, South Parks Rd, Oxford, OX1 3PL

Downloads and Links
Twitter hashtag – #BMCSPostGrad22
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Synopsis
This face to face meeting will comprise of oral and poster presentations from PhD students and post-doctoral workers researching in biological or medicinal chemistry. In addition, the agenda will feature invited keynote speakers from industry and academia.

Who should attend
This conference will be of interest to PhD students, post-doctoral workers, academics and industry workers.

Call for abstracts
Abstract submissions are now closed

Registration
This event is free of charge, however delegates are still required to register. Registration is now closed.

Want to become an RSC member?
To join the RSC in order to qualify for discounted registration fees at all RSC events, please follow this RSC link.

Programme

8.30	Registration and refreshments
09.30	Opening announcements Douglas Williamson, Transition Bio, UK
9.35	Welcome address Stuart Conway, University of Oxford, UK
	First session Chair: Mary Wheldon, University of Dundee, UK
9.40	Keynote lecture: Drug Discovery for Visceral Leishmaniasis Ian Gilbert, University of Dundee, UK
10.10	O1 The development of small molecule inhibitors of the essential Leishmania bromodomain BDF5 Jennifer Carter, University of Oxford, UK
10.30	O2 A High-Throughput Phenotypic Drop-Out Screen for the Identification of Antibiotic Cyclic Peptides Leonie Windeln, University of Southampton, UK
10.50-11.20	Refreshment break and exhibition
11.20	O3 Peroxide-Cleavable Linkers for Antibody-Drug Conjugates Nicola Ashman, University of Cambridge, UK
11.40	Flash oral poster presentations 11.40 FO01 A high-throughput-chemistry, direct-to-biology approach to discover novel reactive fragments targeting SARS-CoV-2 Harry Wilders, GSK, UK 11.42 FO02 Reactive Fragments in Hit Identification for Gasdermin-D Claudine Greenwood, GSK, UK 11.44 FO03 A Reactive Fragment-based PROTAC Platform to Expand the Degradable Proteome Elliot Fellows, University of Strathclyde, UK 11.46 FO04 Multistep High-Throughput Chemistry Direct-to-Biology PROTAC Synthesis Enabled by Late-Stage sp2-sp3 Cross-Coupling Chemistry Rebecca Stevens, University of Strathclyde, UK 11.48 FO05 Novel Cyclosporin-like molecules inhibit the antiviral restriction factor IFITM3 to enhance stem cell gene therapy Valeria Pingitore, University College London, UK 11.50 FO06 Alternative Enzymatic routes to β-lactam Antibiotics Puja Saha, University of Manchester, UK 11.52 FO07 Developing a toolbox to study molecular glue kinetics Bethany Thurairajah, University of Leicester, UK 11.54 FO08 Small molecule tools to target glucose metabolism in Non-Alcoholic Fatty Liver Disease (NAFLD) Nikol Zografou Barredo, University of Newcastle, UK 11.56 FO09 Alpha-helix Mimetics disrupting the RhoA – GEF-H1 interaction for ocular disorders Clara Gathmann, University College London, UK 11.58 FO10 Predicting the Thermodynamics of Water in the KRASG12C Binding Site Daniella Hares, Institute of Cancer Research, UK 12.00 FO11 Norditerpenoid alkaloids and their analogues: Analytical aspects and analogues activity at human α7 nAChR Ashraf M. A. Qasem, University of Bath, UK 12.02 FO12 Towards novel glycosyl inhibitors based on a cyclonucleoside scaffold Ramya K. Nuti, The Queen’s University of Belfast, UK 12.04 FO13 Targeting the cell-adhesion molecule P-selectin glycoprotein ligand-1 with a small molecule inhibitor Ciyana James, The Queen’s University of Belfast, UK 12.06 FO14 Open Source Mycetoma: discovery and development of novel antifungal agents against a neglected mycotic disease Dmitrij Melechov, UCL School of Pharmacy, UK 12.08 FO17 Antimicrobial Peptide Dendrimers for Targeting Cancer and Microbial Infections Arif Khan, University of Karachi, Pakistan
12.20 – 13.35	Lunch, poster session and exhibition
	Second session Chair: Rose Bardell-Cox, Evotec, UK
13.35	Keynote lecture: Adventures with Allosteric Inhibitors of mutant GTPase KRASG12C Sharan Bagal, AstraZeneca, UK
14.05	O4 Accessing New Therapeutics via Water Soluble Disulfide Re-bridging of Antibodies Richard Blackall, University of Strathclyde, UK
14.25	O5 Flipping the Switch: Converting Activators into Degraders to Target Glucose Metabolism Alex Hallatt, University of Newcastle, UK
14.45 – 15.05	Refreshment break and exhibition
	Third session Chair: Katherine Jones, Charles River, UK
15.05	O6 The synthesis of 18 β –Glycyrrhetinic acid derivatives which have increased antibacterial activity against Staphylococcus aureus Maria Odagiu, University of Liverpool, UK
15.25	O7 High throughput screening and identification of synthetically lethal cyclic peptides in MTAP deletion cancer cell lines Monika Papayova, University of Southampton, UK
15.45	Keynote lecture: Patient-first AI: Exscientia’s Approach Anthony Bradley, Exscientia, UK
16.15	Closing remarks John Skidmore, University of Cambridge, UK
16.25	Wine mixer & prizes
17.00	Meeting close

 

Sponsorship opportunities
There is no registration fee for this symposium and we are therefore seeking sponsorship from companies towards running the costs. Please click here to sponsor Postgraduate Symposium XVI.

Exhibition stands are now fully booked.

Sponsors
We are grateful to our confirmed sponsors for their valued support.

Exhibitors
We are grateful to our confirmed exhibitors for their valued support.

Organising Committee

Dave Alker, Dave Alker Associates (Treasurer)
Rose Bardell-Cox, Evotec
Stuart Conway, University of Oxford
Katherine Jones, Charles River
Kate Ogilvy, University of Oxford
John Skidmore, University of Cambridge
Mary Wheldon, University of Dundee
Douglas Williamson, Transition Bio (Chair)

Secretariat Contact and Further Information
Hg3 Conferences Ltd
+44 (0)1423 529333
E-mail