Events

2nd Synthesis in Drug Discovery and Development

Event
2nd Synthesis in Drug Discovery and Development

Dates
Wednesday 4th – Thursday 5th May, 2022

Place
Virtual

Important links
Twitter hashtag – #SDDD22
To submit an abstract, please click here
For delegate registration, please click here
For exhibitor/sponsorship bookings, please click here

Synopsis
Synthesis is at the heart of drug discovery and development. The industry has increasingly demanded higher quality clinical candidates and has sought to exploit less druggable biological targets. Densely functionalised small molecules with a high degree of synthetic complexity are often the result of these demands. Successful programmes therefore require the application of innovative synthesis in all stages of discovery and development. The medicinal chemist’s toolbox is also enhanced by the introduction of novel bioisosteres, often made available only through the application of new synthetic methods. This symposium aimed to celebrate the crucial role of synthesis in the success of drug discovery and development.

Who should attend
Chemists from industry and academia, including synthetic, medicinal and process chemists.

Call for Posters / Abstracts
Abstract submission is now open. Please click here to submit your abstract.
The closing date for submission is Midnight (GMT) Tuesday 30 November, 2021 (oral) and Wednesday 9 February, 2022 (poster).  

Programme
Wednesday 4th May, 2022

13.00Opening Remarks
13.05The impact of Synthetic Chemistry on moving drug discovery programs at speed
David Blakemore, Pfixer
13.45Decarboxylative Radical Functionalisations: Minisci Reactions and Beyond
Ai-Lan Lee, Heriot Watt University
14.25Lighting the way to new disconnections for amines and azacycles
Alex Cresswell, University of Bath
15.05Refreshment Break
15.20Flash poster presentations (Part 1)
15.40Saturated bioisosteres of benzene for medicinal chemistry
Pavel Mykhailiuk, Enamine
16.20Ed Anderson, University of Oxford
17.00Closing Remarks
17.05Networking
18.00Close

Thursday 5th May, 2022

13.00Opening remarks
13.05High throughput experimentation and automation to enable synthesis in fragment based drug discovery
Chloe Townley, Astex
13.45TBC
14.25SynTech: Tackling synthetic challenges and applying synthetic technologies across the drug discovery portfolio
Cara Brocklehurst, Novartis
15.05Refreshment break
15.20 Automating challenging chemistry in flow - The key to unlocking difficult to access libraries in Medicinal Chemistry
Daniel Maddox, Vernalis
16.00 Amino-Oxetanes as Amide Isosteres by an Alternative Defluorosulfonylative Coupling of Sulfonyl Fluorides
Juan J. Rojas, ICL
16.40Late Stage Fluorination with Metal Alkali Fluoride
Veronique Gouverneur, University of Oxford
17.20Poster Awards
17.25Closing Remarks

Registration
Registration is now open, please click here to register

Registration Fees
RSC Member* £50.00
Non-Member £75.00
RSC Student** Member* £20.00
Student** Non-Member £30.00

*Member is a paid-up member of the RSC
** Student rates apply to undergraduate and post-graduate students only, but not post-doctoral

Want to become a member?
To join the RSC in order to qualify for discounted registration fees at all RSC, please follow this RSC link.

Exhibitor/Sponsorship Opportunities
Bookings are now open, please click here to exhibit or sponsor the meeting

There are two exhibitor packages available to book as follows:

Exhibitor package is priced at £60.00 and includes:
– Name and URL link on BMCS event page
– Rolling slides show at the event and a logo with URL in the electronic handbook
– A4 promotional page in the electronic handbook
Note: no delegate registration is included

Exhibitor plus package is priced at £250.00 and includes:
– Name and URL link on BMCS event page
– Rolling slides show at the event and a logo with URL in the electronic handbook
– A4 promotional page in the electronic handbook
– 3 minute pre-recorded video to be played on loop during the breaks
Note: no delegate registration is included

We are also seeking sponsorship from organisations supporting the low registration fees offered to students.  You can support and sponsor this meeting by clicking the booking link above when available.

Our Exhibitors/Sponsors
We are grateful to our confirmed exhibitors/sponsors for their valued support.

Organising Committee
Nadia Ahmad, Charles River
Duncan Hay (chair), Vertex
Martin Swarbrick (treasurer), Cancer Research UK
Andrew Williams, Hon Chairman, RSC BMCS

Secretariat Contact and Further Information
Hg3 Conferences Ltd
+44 (0)1423 529333
E-mail