2nd Synthesis in Drug Discovery and Development

2nd Synthesis in Drug Discovery and Development

Wednesday 4th – Thursday 5th May, 2022

Virtual (Zoom) – Joining instructions and link to the meeting was sent to registered delegates via email on Tuesday 3 May. If you have registered after this date then the link and joining instructions will be included in your registration confirmation email.

Important links
Twitter hashtag – #SDDD22

For delegate registration, please click here
For exhibitor/sponsorship bookings, please click here

Synthesis is at the heart of drug discovery and development. The industry has increasingly demanded higher quality clinical candidates and has sought to exploit less druggable biological targets. Densely functionalised small molecules with a high degree of synthetic complexity are often the result of these demands. Successful programmes therefore require the application of innovative synthesis in all stages of discovery and development. The medicinal chemist’s toolbox is also enhanced by the introduction of novel bioisosteres, often made available only through the application of new synthetic methods. This symposium aimed to celebrate the crucial role of synthesis in the success of drug discovery and development.

Who should attend
Chemists from industry and academia, including synthetic, medicinal and process chemists.

Call for Posters / Abstracts
Abstract submission is now closed.

Wednesday 4th May, 2022

13.00Opening Remarks
13.05The impact of Synthetic Chemistry on moving drug discovery programs at speed
David Blakemore, Pfizer
13.45Decarboxylative Radical Functionalisations: Minisci Reactions and Beyond
Ai-Lan Lee, Heriot Watt University
14.25Lighting the way to new disconnections for amines and azacycles
Alex Cresswell, University of Bath
15.05Refreshment Break
15.30Flash poster presentations
15.34Unusual substituents for medicinal chemistry
Pavel Mykhailiuk, Enamine
16.14Late Stage Fluorination with Metal Alkali Fluoride
Veronique Gouverneur, University of Oxford
16.54Closing Remarks

Thursday 5th May, 2022

13.00Opening remarks
13.05High throughput experimentation and automation to enable synthesis in fragment based drug discovery
Chloe Townley, Astex
13.45Implementation of High Throughput Experimentation in Oncology, Discovery Chemistry at AstraZeneca
Gary Fairley, AstraZeneca
14.25SynTech: Tackling synthetic challenges and applying synthetic technologies across the drug discovery portfolio
Cara Brocklehurst, Novartis
15.05Refreshment break
15.30 Automating challenging chemistry in flow - The key to unlocking difficult to access libraries in Medicinal Chemistry
Daniel Maddox, Vernalis
16.10 Amino-Oxetanes as Amide Isosteres by an Alternative Defluorosulfonylative Coupling of Sulfonyl Fluorides
Juan J. Rojas, ICL
16.50Exploring and Exploiting Propellanes
Ed Anderson, University of Oxford
17.30Poster Awards
17.35Closing Remarks

Registration is now open, please click here to register

Registration Fees
RSC Member* £50.00
Non-Member £75.00
RSC Student** Member* £20.00
Student** Non-Member £30.00

*Member is a paid-up member of the RSC
** Student rates apply to undergraduate and post-graduate students only, but not post-doctoral

Want to become a member?
To join the RSC in order to qualify for discounted registration fees at all RSC, please follow this RSC link.

Exhibitor/Sponsorship Opportunities
Bookings are now open, please click here to exhibit or sponsor the meeting

There are two exhibitor packages available to book as follows:

Exhibitor package is priced at £60.00 and includes:
– Name and URL link on BMCS event page
– Rolling slides show at the event and a logo with URL in the electronic handbook
– A4 promotional page in the electronic handbook
Note: no delegate registration is included

Exhibitor plus package is priced at £250.00 and includes:
– Name and URL link on BMCS event page
– Rolling slides show at the event and a logo with URL in the electronic handbook
– A4 promotional page in the electronic handbook
– 3 minute pre-recorded video to be played on loop during the breaks
Note: no delegate registration is included

We are also seeking sponsorship from organisations supporting the low registration fees offered to students.  You can support and sponsor this meeting by clicking the booking link above when available.

Our Exhibitors/Sponsors
We are grateful to our confirmed exhibitors/sponsors for their valued support.




Organising Committee
Nadia Ahmad, Charles River
Duncan Hay (chair), Vertex
Martin Swarbrick (treasurer), Ryvu Therapeutics
Andrew Williams, Hon Chairman, RSC BMCS

Secretariat Contact and Further Information
Hg3 Conferences Ltd
+44 (0)1423 529333