2nd Synthesis in Drug Discovery and Development
Event
2nd Synthesis in Drug Discovery and Development
Dates
Wednesday 4th – Thursday 5th May, 2022
Place
Virtual (Zoom) – Joining instructions and link to the meeting was sent to registered delegates via email on Tuesday 3 May. If you have registered after this date then the link and joining instructions will be included in your registration confirmation email.
Important links
Twitter hashtag – #SDDD22
For delegate registration, please click here
For exhibitor/sponsorship bookings, please click here
Synopsis
Synthesis is at the heart of drug discovery and development. The industry has increasingly demanded higher quality clinical candidates and has sought to exploit less druggable biological targets. Densely functionalised small molecules with a high degree of synthetic complexity are often the result of these demands. Successful programmes therefore require the application of innovative synthesis in all stages of discovery and development. The medicinal chemist’s toolbox is also enhanced by the introduction of novel bioisosteres, often made available only through the application of new synthetic methods. This symposium aimed to celebrate the crucial role of synthesis in the success of drug discovery and development.
Who should attend
Chemists from industry and academia, including synthetic, medicinal and process chemists.
Call for Posters / Abstracts
Abstract submission is now closed.
Programme
Wednesday 4th May, 2022
| 13.00 | Opening Remarks |
| 13.05 | The impact of Synthetic Chemistry on moving drug discovery programs at speed David Blakemore, Pfizer |
| 13.45 | Decarboxylative Radical Functionalisations: Minisci Reactions and Beyond Ai-Lan Lee, Heriot Watt University |
| 14.25 | Lighting the way to new disconnections for amines and azacycles Alex Cresswell, University of Bath |
| 15.05 | Refreshment Break |
| 15.30 | Flash poster presentations |
| 15.34 | Unusual substituents for medicinal chemistry Pavel Mykhailiuk, Enamine |
| 16.14 | Late Stage Fluorination with Metal Alkali Fluoride Veronique Gouverneur, University of Oxford |
| 16.54 | Closing Remarks |
| 17.00 | Close |
Thursday 5th May, 2022
| 13.00 | Opening remarks |
| 13.05 | High throughput experimentation and automation to enable synthesis in fragment based drug discovery Chloe Townley, Astex |
| 13.45 | Implementation of High Throughput Experimentation in Oncology, Discovery Chemistry at AstraZeneca Gary Fairley, AstraZeneca |
| 14.25 | SynTech: Tackling synthetic challenges and applying synthetic technologies across the drug discovery portfolio Cara Brocklehurst, Novartis |
| 15.05 | Refreshment break |
| 15.30 | Automating challenging chemistry in flow - The key to unlocking difficult to access libraries in Medicinal Chemistry Daniel Maddox, Vernalis |
| 16.10 | Amino-Oxetanes as Amide Isosteres by an Alternative Defluorosulfonylative Coupling of Sulfonyl Fluorides Juan J. Rojas, ICL |
| 16.50 | Exploring and Exploiting Propellanes Ed Anderson, University of Oxford |
| 17.30 | Poster Awards |
| 17.35 | Closing Remarks |
Registration
Registration is now open, please click here to register
Registration Fees
RSC Member* £50.00
Non-Member £75.00
RSC Student** Member* £20.00
Student** Non-Member £30.00
*Member is a paid-up member of the RSC
** Student rates apply to undergraduate and post-graduate students only, but not post-doctoral
Want to become a member?
To join the RSC in order to qualify for discounted registration fees at all RSC, please follow this RSC link.
Exhibitor/Sponsorship Opportunities
Bookings are now open, please click here to exhibit or sponsor the meeting
There are two exhibitor packages available to book as follows:
Exhibitor package is priced at £60.00 and includes:
– Name and URL link on BMCS event page
– Rolling slides show at the event and a logo with URL in the electronic handbook
– A4 promotional page in the electronic handbook
Note: no delegate registration is included
Exhibitor plus package is priced at £250.00 and includes:
– Name and URL link on BMCS event page
– Rolling slides show at the event and a logo with URL in the electronic handbook
– A4 promotional page in the electronic handbook
– 3 minute pre-recorded video to be played on loop during the breaks
Note: no delegate registration is included
We are also seeking sponsorship from organisations supporting the low registration fees offered to students. You can support and sponsor this meeting by clicking the booking link above when available.
Our Exhibitors/Sponsors
We are grateful to our confirmed exhibitors/sponsors for their valued support.
Organising Committee
Nadia Ahmad, Charles River
Duncan Hay (chair), Vertex
Martin Swarbrick (treasurer), Ryvu Therapeutics
Andrew Williams, Hon Chairman, RSC BMCS
Secretariat Contact and Further Information
Hg3 Conferences Ltd
+44 (0)1423 529333
E-mail
